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Periviscerokinin (Pea-PVK): A novel myotropic neuropeptide from the perisympathetic organs of the American cockroach
| Content Provider | Semantic Scholar |
|---|---|
| Author | Predel, Reinhard Linde, Dirk Van Der Rapus, Jürgen Vettermann, Stefan Penzlin, Heinz |
| Copyright Year | 1995 |
| Abstract | A myotropic neuropeptide was isolated from extracts of 1000 abdominal perisympathetic organs of males of the cockroach, Periplaneta americana. This peptide, termed periviscerokinin, has excitatory actions on the hyperneural muscle of Periplaneta americana. After peptide sequence analysis and mass spectrometry, the structure of this peptide was confirmed by chemical synthesis and bioassay to be Gly-Ala-Ser-Gly-Leu-Ile-Pro-Val-Met-Arg-Asn-NH2. This sequence is different from the other known myotropic peptides in insects. The threshold concentration for stimulatory effects of the synthetic peptide on the isolated hyperneural muscle was about 10(-9) M, suggesting a physiological role as a neurohormone. |
| Starting Page | 61 |
| Ending Page | 66 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0196-9781(94)00144-U |
| PubMed reference number | 7716075 |
| Journal | Medline |
| Volume Number | 16 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/019697819400144U |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/019697819400144U?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0196-9781%2894%2900144-U |
| Journal | Peptides |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
