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Stereoselective synthesis of sugar-fused (or 1,2-annulated) isochromans and isochromanones by using oxa-Pictet-Spengler reaction.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Verma, Ashish Kumar Chennaiah, Ande Dubbu, Sateesh Vankar, Yashwant D. |
| Copyright Year | 2018 |
| Abstract | A highly efficient stereoselective synthesis of sugar fused 1,2-annulated isochromans is reported by utilizing the oxa-Pictet-Spengler cyclization reaction. The process is found to be very general as both glucal and galactal derived C2-hydroxy-α-C-aryl glycosides lead to the target molecules in good yields. The utility of this strategy was extended to the synthesis of sugar fused isochromanones, which are bergenin type molecules. |
| Starting Page | 8258 |
| Ending Page | 8262 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c8ob01698d |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c8/ob/c8ob01698d/c8ob01698d1.pdf |
| PubMed reference number | 30204196 |
| Alternate Webpage(s) | https://doi.org/10.1039/c8ob01698d |
| Journal | Medline |
| Volume Number | 16 |
| Issue Number | 37 |
| Journal | Organic & biomolecular chemistry |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |