NDLI: Prevalência de defeitos de fechamento de tubo neural no Vale do Paraíba, São Paulo

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Prevalência de defeitos de fechamento de tubo neural no Vale do Paraíba, São Paulo

Content Provider	Semantic Scholar
Author	Nascimento, Luiz Fernando Costa
Copyright Year	2008
Abstract	OBJECTIVE: To estimate the prevalence of neural tube defects in Vale do Paraiba, Sao Paulo, Brazil, and to identify possible maternal and neonatal variables associated with these defects. METHODS: This cross-sectional study used secondary records of the Health Department of Sao Paulo State related live births during 2004 in Vale do Paraiba, Sao Paulo, Brazil. This region has 35 cities and 2 million inhabitants. Anencephaly, encephalocele and spina bifida (myelocele and myelomeningocele) were considered as neural tube defects. The following maternal variables were analyzed: age, educational level, race, number of born alive and stillborn infants and prenatal visits. Neonatal variables were: birth weight, gestational age and Apgar score. Numerical variables were compared by Student t test, and Odds Ratio values were obtained with the 95% confidence interval. RESULTS: The analysis was performed based on 33,653 records of born alive infants. Twenty-three infants with spina bifida were identified, with an estimated prevalence of 1.13 cases for each 1,000 live births. The presence of neural tube defects was associated to low birth weight, prematurity and low Apgar score. CONCLUSIONS: The estimated prevalence of neural tube defects in this region of Sao Paulo was lower than others reported in previous Brazilian studies. These defects were associated with low birth weight, prematurity and respiratory depression at birth.
Starting Page	372
Ending Page	377
Page Count	6
File Format	PDF HTM / HTML
DOI	10.1590/S0103-05822008000400011
Volume Number	26
Alternate Webpage(s)	http://www.scielo.br/pdf/rpp/v26n4/a11v26n4.pdf
Alternate Webpage(s)	https://doi.org/10.1590/S0103-05822008000400011
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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