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Neonatal screening for inborn errors of metabolism
| Content Provider | Semantic Scholar |
|---|---|
| Author | Cunningham, George L. Green, Nancy S. |
| Copyright Year | 2005 |
| Abstract | In their Comment on rabies encephalitis (Mar 12, p 921), François Sellal and Françoise Stoll-Keller state that the UK is said never to have had an indigenous case of rabies, although they do mention the recent bat-acquired case in Scotland. In fact, rabies was endemic in the UK throughout the 18th and 19th centuries, and probably before that. Packs of semi-wild stray dogs were the main, if not the only, reservoir of infection, and domestic dogs were infected from this source. Cases subsequently occurred in hunting dogs and entire packs had to be destroyed. One such outbreak in a pack of stag hounds is recorded by Scarth-Dixon. Human cases, acquired from dog bites, occurred on an almost annual basis, and rabies was only brought under control after the 1867 Metropolitan Streets Act and the 1897 General Rabies Order, Muzzling Order for the Metropolitan Police District, and Importation of Dogs Order, acts which enforced the shooting of stray dogs, strict muzzling of all pet dogs, and draconian quarantine regulations. The last locally acquired case and death from human rabies was in Wales in 1902, and canine rabies also became extinct after this time. Before the 20th century, UK fox populations did not become urbanised and the rural fox population seems to have been too low to sustain infection in this species. This is the likely reason for the rapid eradication of rabies in the UK. Rabies again became endemic in dogs in limited areas of the UK in 1918, when soldiers returning from the First World War brought home their infected pet dogs from France, evading importation quarantine regulations. No human cases occurred this time and the outbreak was rapidly brought under control, the last recorded case being in 1922. |
| Starting Page | 2175 |
| Ending Page | 2176 |
| Page Count | 2 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/S0140-6736(05)66770-0 |
| PubMed reference number | 15978917 |
| Journal | Medline |
| Volume Number | 365 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/S0140673605667700 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/S0140673605667700?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/S0140-6736%2805%2966770-0 |
| Journal | The Lancet |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
