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Establishing a knowledge trail from molecular experiments to clinical trials.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Yong, May González-Beltrán, Alejandra N. Begent, Richard H. J. |
| Copyright Year | 2011 |
| Abstract | During the development cycle of a new antibody therapy, the therapeutic agent will be tested on subsequently more biologically complex models. New experiments' designs are based upon data gathered from prior models. New researchers who inherit the data and researchers from groups with different cultures or expertise are often called upon to interpret these data. Experiments which are not recorded consistently or employ ambiguous terminology can make interpreting these results difficult. The researcher who had originally collected the data may not be at hand to correct any misunderstanding or offer clarification and data can be unknowingly misused. This introduces an element of risk into the therapy development process. We have developed a reporting guideline for recording therapy experiments. This guideline consists of a checklist of data to be recorded from antibody therapy experiments performed in molecular, cellular, animal and clinical model. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.nbt.2011.03.016 |
| PubMed reference number | 21473938 |
| Journal | Medline |
| Volume Number | 28 |
| Issue Number | 5 |
| Alternate Webpage(s) | http://www0.cs.ucl.ac.uk/staff/a.gonzalezbeltran/pubs/newbio2011.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/j.nbt.2011.03.016 |
| Journal | New biotechnology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
