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Synthesis of 5‐epi‐Isofagomine via Asymmetric Chelate–Enolate Claisen Rearrangement
| Content Provider | Semantic Scholar |
|---|---|
| Author | Schneider, Christiane Kazmaier, Uli |
| Copyright Year | 1998 |
| Abstract | Polyhydroxylated piperidines are an interesting class of glycosidase inhibitors. Chelate enolate Claisen rearrangement of N-protected chiral amino acid esters gives rise to γ,δ-unsaturated amino acids, which can be converted to this type of alkaloids. The potential glycosidase inhibitor 5-epi-isofagomine (5) was synthesized by this approach in a highly stereoselective fashion. |
| Starting Page | 1155 |
| Ending Page | 1159 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/(SICI)1099-0690(199806)1998:6<1155::AID-EJOC1155>3.0.CO;2-G |
| Volume Number | 1998 |
| Alternate Webpage(s) | https://www.uni-saarland.de/fileadmin/user_upload/Professoren/fr81_ProfKazmaier/Abstracts/29.pdf |
| Alternate Webpage(s) | https://doi.org/10.1002/%28SICI%291099-0690%28199806%291998%3A6%3C1155%3A%3AAID-EJOC1155%3E3.0.CO%3B2-G |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |