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Development of Antibody‐Directed Therapies: Quo Vadis?
| Content Provider | Semantic Scholar |
|---|---|
| Author | Rodrigues, Tiago Bernardes, Gonçalo J. L. |
| Copyright Year | 2018 |
| Abstract | Less is more: The efficacy of antibody-drug conjugates (ADCs) for cancer therapy is traditionally associated with cleavable linkers for payload release. Evidence now suggests that simpler constructs without cleavable moieties can afford more stable and effective ADCs. |
| Starting Page | 2032 |
| Ending Page | 2034 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/anie.201712185 |
| Alternate Webpage(s) | http://gbernardeslab.com/wp/wp-content/uploads/2018/03/82.pdf |
| Alternate Webpage(s) | http://gbernardeslab.com/wp/wp-content/uploads/2018/01/81.pdf |
| PubMed reference number | 29341367 |
| Alternate Webpage(s) | https://doi.org/10.1002/anie.201712185 |
| Journal | Medline |
| Volume Number | 57 |
| Journal | Angewandte Chemie |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |