Loading...
Please wait, while we are loading the content...
Similar Documents
Anti-inflammatory and Analgesic Activities of Holarrhena antidysenterica Wall. Leaf Extract in Experimental Animal Models
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ganapathy, P. S. S. Ramachandra, Yl Rai, Padmalatha |
| Copyright Year | 2010 |
| Abstract | The methanolic extract of Holarrhena antidysenterica Wall. leaf was subjected to pharmacological screening using various animal models. The extract showed anti-inflammatory activity in the carrageenan-induced rat paw edema model method and analgesic activity when tested in the acetic acid–induced writhing test in Swiss albino mice and tail-flick response tests in Swiss albino rats. The plant extract, at doses of 100 and 200 mg/kg body weight, showed significant inhibition of rat paw edema at the fourth hour after carrageenan injection and peripheral as well as central analgesic activity by oral route. Therefore, the current study indicates that the methanol extract of H. antidysenterica leaf has significant anti-inflammatory and peripheral and central analgesic activity. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.globalsciencebooks.info/Online/GSBOnline/images/2010/IJBPS_4(1&2)/IJBPS_4(2)101-103o.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
