Evolução da resistência de Pseudomonas aeruginosa e Acinetobacter baumannii em unidades de terapia intensiva

Content Provider	Semantic Scholar
Author	Nóbrega, Marciano De Sousa Filho, José Rodrigues Do Carmo Pereira, Milca Severino
Copyright Year	2013
Abstract	ABSTRACT The objective of this study was to describe the susceptibility of A. baumannii and P. aeruginosa, analyze the trend in bacterial resistance and use of antimicrobial agents. This retrospective, descriptive, cross-sectional study was performed in the adult intensive care units of a large-scale public teaching hospital, within the Brazilian Unified Health System (SUS). A total of 121 cases of infection by P. aeruginosa and A. baumannii were identified. A high mean initial resistance rate was observed for both microorganisms. A significant increase was observed in resistance to amikacin in A. baumannii . There was an increase in the consumption of amikacin, imipenem, and piperacillin-tazobactam in P. aeruginosa infections, and of imipenem in A. baumannii infections . No correlation was found between bacterial resistance and antimicrobial use. Higher mortality rates and longer length of stay were observed in the studied group, and bacterial resistance was high. Furthermore, there was an increase in the use of amikacin, imipenem and piperacillin-tazobactam. Descriptors: Pseudomonas aeruginosa ; Acinetobacter baumannii ; Drug Resistance; Anti-Infective Agents; Cross Infection.
Starting Page	694
Ending Page	701
Page Count	8
File Format	PDF HTM / HTML
DOI	10.5216/ree.v15i3.22031
Volume Number	15
Alternate Webpage(s)	https://www.revistas.ufg.br/fen/article/download/22031/15495
Alternate Webpage(s)	https://doi.org/10.5216/ree.v15i3.22031
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article