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Green glycosylation using ionic liquid to prepare alkyl glycosides for studying carbohydrate–protein interactions by SPR
| Content Provider | Semantic Scholar |
|---|---|
| Author | Muñoz, F. Javier André, Sabine Gabius, Hans-Joachim Sinisterra, José V. Hernáiz, María José Linhardt, Robert J. |
| Copyright Year | 2009 |
| Abstract | Several simple glycosides of D-glucose (Glc) and N-acetyl-D-galactosamine (GalNAc) were prepared in a single step glycosylation reaction using unprotected and unactivated sugar donors. The resulting GalNAc glycoside, containing a bifunctional linker, was used to immobilize this glycoconjugate to a self assembled monolayer on a gold biosensor chip. Surface plasmon resonance (SPR) experiments demonstrated that this immobilized glycoconjugate bound to GalNAc specific lectin, Viscum album agglutinin. |
| Starting Page | 373 |
| Ending Page | 379 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/B814171A |
| Alternate Webpage(s) | http://www-heparin.rpi.edu/main/files/papers/464.pdf%0A |
| Alternate Webpage(s) | https://doi.org/10.1039/B814171A |
| Volume Number | 11 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |