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Incorporating Parameter Uncertainty in Bayesian Segmentation Models: Application to Hippocampal Subfield Volumetry
| Content Provider | Semantic Scholar |
|---|---|
| Author | Iglesias, Juan Eugenio Sabuncu, Mert R. Leemput, Koenraad Van |
| Copyright Year | 2012 |
| Abstract | Many successful segmentation algorithms are based on Bayesian models in which prior anatomical knowledge is combined with the available image information. However, these methods typically have many free parameters that are estimated to obtain point estimates only, whereas a faithful Bayesian analysis would also consider all possible alternate values these parameters may take. In this paper, we propose to incorporate the uncertainty of the free parameters in Bayesian segmentation models more accurately by using Monte Carlo sampling. We demonstrate our technique by sampling atlas warps in a recent method for hippocampal subfield segmentation, and show a significant improvement in an Alzheimer's disease classification task. As an additional benefit, the method also yields informative "error bars" on the segmentation results for each of the individual sub-structures. |
| Starting Page | 7656 |
| Ending Page | 7662 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.nmr.mgh.harvard.edu/~iglesias/pdf/MICCAI2012_pre.pdf |
| Alternate Webpage(s) | http://ftp.nmr.mgh.harvard.edu/pub/articles/2012/2012_-_Iglesias,_Sabuncu,_Van_Leemput_-_Medical_image_computing_and_computer-assisted_intervention_MICCAI.pdf |
| Alternate Webpage(s) | https://doi.org/10.1007/978-3-642-33454-2_7 |
| Alternate Webpage(s) | http://people.csail.mit.edu/msabuncu/SelectPublications/IglesiasMICCAI2012.pdf |
| Alternate Webpage(s) | http://nmr.mgh.harvard.edu/~koen/IglesiasMICCAI2012.pdf |
| Alternate Webpage(s) | https://surfer.nmr.mgh.harvard.edu/pub/articles/2012/2012_-_Iglesias,_Sabuncu,_Van_Leemput_-_Medical_image_computing_and_computer-assisted_intervention_MICCAI.pdf |
| Alternate Webpage(s) | http://freesurfer.net/pub/articles/2012/2012_-_Iglesias,_Sabuncu,_Van_Leemput_-_Medical_image_computing_and_computer-assisted_intervention_MICCAI.pdf |
| PubMed reference number | 23286113v1 |
| DOI | 10.1007/978-3-642-33454-2_7 |
| Journal | MICCAI |
| Volume Number | 15 |
| Part | 3 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Alzheimer's Disease Bayesian network Cervical Atlas Estimated Information Leucaena pulverulenta Monte Carlo method Sampling (signal processing) Sampling - Surgical action algorithm biologic segmentation disease classification volumetry |
| Content Type | Text |
| Resource Type | Article |
