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Alexis Carrel And
| Content Provider | Semantic Scholar |
|---|---|
| Author | Carrel, Alexis Ebeling, Albert H. |
| Copyright Year | 2003 |
| Abstract | A few years ago, monocytes in pure culture were found to metamorphose under cer ta in conditions into elongated or stellate cells, and to assume the appearance of fibroblasts from which they became indistinguishable? The processes of the t ransformed cells were long and sharp, and did no t show any of the movements tha t characterize the pseudopods of monocytes ; their nucleus was oval with one or two nucleoli; their cytoplasm contained a number of granules tha t took up neutra l red in the same manner as do the fibroblasts kept in pure culture for over 13 years. As no permanent strain of these cells was obtained, i t was not quite certain tha t the monocytes had metamorphosed into true fibroblasts. Bu t the reali ty of such a t ransformation has been demonst ra ted recent ly by Fischer, 2 who succeeded in obtaining a pe rmanen t strain of fibroblasts from a culture of leucocytes. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://jem.rupress.org/content/jem/43/4/461.full.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |