Effects of risperidone, an atypical antipsychotic drug, on excitatory synaptic responses in the perforant path–dentate gyrus pathway in chronically prepared rabbits

Content Provider	Semantic Scholar
Author	Kubota, Toshihiko Jibiki, Itsuki Kurokawa, Sonoko
Copyright Year	2001
Abstract	The effects of an atypical antipsychotic drug, risperidone, were examined on excitatory synaptic responses in the dentate gyrus by single electrical stimulations to the perforant path and the induction of long-term potentiation (LTP) in this pathway in chronically prepared rabbits. Any of 0.5, 1.0 and 2.0 mg/kg doses of risperidone intraperitoneally injected had virtually no effect on the excitatory synaptic responses. However, these three doses of risperidone dose-dependently suppressed the LTP induction.
Starting Page	237
Ending Page	242
Page Count	6
File Format	PDF HTM / HTML
DOI	10.1016/S0091-3057(01)00609-8
PubMed reference number	11701193
Journal	Medline
Volume Number	70
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/S0091305701006098
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/S0091305701006098?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://doi.org/10.1016/S0091-3057%2801%2900609-8
Journal	Pharmacology Biochemistry and Behavior
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article