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Chimeric antigen receptors targeting b-cell maturation antigen
| Content Provider | Semantic Scholar |
|---|---|
| Author | Кохендерфер, Джеймс Нобл |
| Copyright Year | 2013 |
| Abstract | FIELD: biotechnology. SUBSTANCE: present invention relates to an isolated nucleic acid molecule encoding a chimeric antigen receptor (CAR) directed against a B cell maturation antigen (BCMA). Present invention also discloses host cells, such as T cells or natural killer (NK cells) expressing CAR, and refers to methods for destroying multiple myeloma cells using these cells. EFFECT: present invention makes it possible to expand the arsenal of agents for the treatment of multiple myeloma. 22 cl, 9 dwg, 4 tbl, 6 ex |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://patentimages.storage.googleapis.com/8c/7e/1d/9b2b25ff892f0f/WO2013154760A1.pdf |
| Alternate Webpage(s) | https://patentimages.storage.googleapis.com/39/a2/0b/c989463f797b68/US20150051266A1.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |