Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) Applications in Bacteriology: brazilian contributions

Content Provider	Semantic Scholar
Author	Pellegrino, Flavia Chagas, Thiago Pavoni Gomes Alves, Maria Silvana Carvalho-Assef, Ana Paula D’ Alincourt Chapeaurouge, Alexander D. Asensi, Marise Dutra
Copyright Year	2018
Abstract	Among its innumerous applications in Bacteriology, the M atrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) technique is evolving as a powerful tool for bacterial identification and antimicrobial resistance investigation. Publications have evaluated the MALDI-TOF MS performance in the identification of a series of bacterial pathogens, including the most common severe infectious agents, emergent pathogens involved with outbreaks of healthcare-associated infections, rare pathogens, and those whose isolation in culture media is difficult. As compared to conventional methods of bacterial identification, MALDI-TOF MS has proven to be a fast, accurate and cost-effective technique. Currently, MALDI-TOF MS has been used in antimicrobial resistance studies, since it has shown to be an efficient tool in detecting specific resistance mechanisms in bacteria, such as beta-lactamases production, for example. Here, we describe the advances in this growing field of mass spectrometry applied to Bacteriology, including Brazilian contributions.
Starting Page	285
Ending Page	294
Page Count	10
File Format	PDF HTM / HTML
Volume Number	43
Alternate Webpage(s)	https://periodicos.ufjf.br/index.php/hurevista/article/download/2859/pdf/
Alternate Webpage(s)	https://doi.org/10.34019/1982-8047.2017.v43.2859
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article