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Terapia con tiosolfato di sodio e oro: studio osservazionale, aperto, multicentrico in pazienti con artrite reumatoide seguiti per due anni Sodium-gold thyosolphatum therapy: an open, viewed, multicenter trial in rheumatoid arthritis patients followed for two years
| Content Provider | Semantic Scholar |
|---|---|
| Author | Amoresano, C. Balzarini, Piera Broggini, Massimo Buratti, Laura Calcagnile, Fabio Ciocci, Alessandro Ferri, Sandrine Fichera, Claudio Fumagalli, Mario Muratore, Maurizio Nitti, Fabio Peruz, Giovanni Romagnoni, G. G. |
| Copyright Year | 2002 |
| Abstract | SUMMARY Objective: To evaluate if parenteral gold-therapy with Sodium-Gold Thyosolphatum is effective and safe for the treat- ment of rheumatoid arthritis we began an open, multicenter trial. Methods: 126 rheumatoid arthritis patients were treated with Sodium-Gold Thyosolphatum for two years. Efficacy, quality of life, progression of joint damage, inflammatory parameters and side effects were evaluated. Results: Gold salts reduced joint inflammation and improved subjective and objective symptoms, quality of life and activity of illness within 6 months. Side effects appeared in 13,8% of all cases and regressed, promptly, when gold therapy stopped. The poor efficacy caused the interruption and the change from the gold therapy to others disease- modifying anti-rheumatic drugs (DMRDs) in 17,8 % of the patients. Conclusions: The follow-up showed Sodium-Gold Thyosolphatum was effective in Rheumatoid Arthritis and the sur- vival in therapy was of 77,8% to one year and of 68,4% to two years. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.reumatismo.org/index.php/reuma/article/download/reumatismo.2002.251/76 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |