NDLI: Moment closure approximations for stochastic kinetic models with rational rate laws.

Content Provider	Semantic Scholar
Author	Milner, Peter Gillespie, Colin S. Wilkinson, Darren J.
Copyright Year	2011
Abstract	Stochastic models are often used when modelling chemical species that have low numbers of molecules. However, as these models become large, it can become computationally expensive to simulate even a single realisation of the system since even efficient simulation techniques have a high computational cost. One possible technique to approximate the stochastic system is moment closure. The moment closure approximation is used to provide analytic approximations to non-linear stochastic models. Until now, this approximation has only been applied to models with polynomial rate laws. In this paper we extend the moment closure method to cover models with rational rate laws.
Starting Page	99
Ending Page	104
Page Count	6
File Format	PDF HTM / HTML
DOI	10.1016/j.mbs.2011.02.006
PubMed reference number	21338614
Journal	Medline
Volume Number	231
Issue Number	2
Alternate Webpage(s)	http://www.mas.ncl.ac.uk/~ncsg3/content/papers/moment11.pdf
Alternate Webpage(s)	https://doi.org/10.1016/j.mbs.2011.02.006
Journal	Mathematical biosciences
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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Moment closure approximations for stochastic kinetic models with rational rate laws.