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Kinesin and dynein superfamily proteins and the mechanism of organelle transport.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Hirokawa, Nobutaka |
| Copyright Year | 1998 |
| Abstract | Cells transport and sort proteins and lipids, after their synthesis, to various destinations at appropriate velocities in membranous organelles and protein complexes. Intracellular transport is thus fundamental to cellular morphogenesis and functioning. Microtubules serve as a rail on which motor proteins, such as kinesin and dynein superfamily proteins, convey their cargoes. This review focuses on the molecular mechanism of organelle transport in cells and describes kinesin and dynein superfamily proteins. |
| Starting Page | 395 |
| Ending Page | 401 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://fire.biol.wwu.edu/cmoyer/zztemp_fire/biol201_F99/papers/motors98.pdf |
| PubMed reference number | 9438838v1 |
| Volume Number | 279 |
| Issue Number | 5350 |
| Journal | Science |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Ankyrins Antineutrophil Cytoplasmic Antibodies Cytoplasmic Dyneins Cytoskeletal Filaments Dynein ATPase Intracellular Transport Membrane Protein Traffic Microtubules Mobility aid Molecular Genetics (discipline) Organelles SLC3A2 gene Signal Transduction Tissue membrane cell morphogenesis cytoplasmic dynein heavy chain dynactin subunit 1 |
| Content Type | Text |
| Resource Type | Article |