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Stability Indicating Reverse phase Liquid chromatographic Method for the Determination of Metoprolol succinate in Pharmaceutical Dosage Forms
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kalisetty, Sainath Reddy, Thummala Sreenivasulu Reddy, Annarapu Malleswara Palnati, Joy Babu Rao, Dama Venugopala Manikandan, Ramu |
| Copyright Year | 2012 |
| Abstract | This paper describes the development and validation of simple, Robust, Rugged and stability indicating liquid chromatographic analytical method for the Assay of Metoprolol succinate in Pharmaceutical Dosage form s. The method employs a Waters X-Terra RP 18(150mm X 4.6 m m, 5 μm particle size) column with UV detection at 240 nm. Method was designed to extract the drug substan ce Metoprolol succinate in any type of matrix formu lations available in the market. This method can be used fo r Quality control assay of Metoprolol in finished dosage forms and for stability studies as the method separates a ll impurities and degradation products from Metopro lol. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.jocpr.com/articles/stability-indicating-reverse-phase-liquid-chromatographic-method-for-thedetermination-of-metoprolol-succinate-in-pharmac.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |