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AgNPs: The New Allies Against S. Mutans Biofilm - A Pilot Clinical Trial and Microbiological Assay.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Freire, Priscila L. L. Albuquerque, Allan Dos Reis Sampaio, Fábio Correia Galembeck, André Flores, Miguel Angel Pelagio Stamford, Thayza Christina Montenegro Rosenblatt, Aronita |
| Copyright Year | 2017 |
| Abstract | The purpose of this study was to evaluate the antimicrobial properties of a new formulation containing silver nanoparticles, named Nano Silver Fluoride (NSF), to inhibit Streptococcus mutans biofilm formation on children's dental enamel. The variations in dental biofilm pH and in the Simplified-Oral-Hygiene-Index (OHI-S) also were evaluated after the treatment with NSF. This was a randomized, double-blind, crossover and prospective pilot clinical trial study in which 12 schoolchildren, aged between 7-8 years, had their dental enamel treated with two solutions: S1 - Nano Silver Fluoride and S2 - negative control (saline solution), in different experimental moments. The dental biofilm adhered to enamel treated with NSF had lower values of S. mutans viability (absorbance) and colony forming units (CFU) than the S0 (baseline) and S2. There was a statistically significant difference between the OHI-S mean values of S0 and S1. There were no differences between the biofilm pH (both before and after the use of the test substances) and among the different groups. These properties suggest that NSF has bactericidal effect against S. mutans biofilm and it may be used for clinical control and prevention of dental biofilm formation. |
| Starting Page | 417 |
| Ending Page | 422 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.scielo.br/pdf/bdj/v28n4/1806-4760-bdj-28-04-417.pdf |
| PubMed reference number | 29160391v1 |
| Alternate Webpage(s) | https://doi.org/10.1590/0103-6440201600994 |
| DOI | 10.1590/0103-6440201600994 |
| Journal | Brazilian dental journal |
| Volume Number | 28 |
| Issue Number | 4 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Colony-forming unit Dental Enamel Microbial Biofilms Name Nephrogenic Systemic Fibrosis Saline Solution Silver Sodium Fluoride 0.0024 MG/MG Toothpaste Theileria mutans Ab:Titr:Pt:Ser:Qn biofilm formation substance |
| Content Type | Text |
| Resource Type | Article |
