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Effects of diet on rat intestinal soluble hexokinase and fructokinase activities.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Quill, Helen Isselbacher, Kurt J. |
| Copyright Year | 1971 |
| Abstract | WEISER,MILTON M., HELEN QUILL, AND KURT J. ISSELBACHER. effects c~f diet on rat intestinal soluble hexokinase and fructokinase activities. Am. J. Physiol. 221(3) : 844-849. 1971 .-The effects of diet on rat intestinal hexokinase activity, hexokinase isozymes, and fructokinase activity were evaluated by separation of these enzymes with DEAEcellulose chromatography. Casein noncarbohydrate diets decreased intestinal hexokinase activity when compared to starved animals. High-fructose diets did not increase hexokinase activity. High-glucose or high-sucrose diets increased hexokinase activity but only as compared to the casein-fed animals. A major effect of high-glucose diets was a relative increase in jejunal type II hexokinase over type I. The increased ratio of type 11 over trpe I hexokinase appeared to be confined to the upper absorbing cells of the villus, suggesting a noninductive effect of high-glucose concentrations. 7j6, IV (glucokinase) was never detected. Hexokinase activity w’as consistently higher in the ileum while fructokinase activity was higher in the jejunum. Starved animals and casein noncarbohydrate-fed animals had equally low fructokinase activity. All three high-carbohydrate diets (glucose, fructose, and sucrose) increased fructokinase activity, though the increase was higher on the high-fructose and high-sucrose diets. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://ajplegacy.physiology.org/content/221/3/844?ijkey=375e0412023141542eed611970bcf7698c2712e8&keytype2=tf_ipsecsha |
| Alternate Webpage(s) | http://ajplegacy.physiology.org/content/221/3/844?ijkey=34912c8b50057b597104004d118396393098e57f&keytype2=tf_ipsecsha |
| PubMed reference number | 5570341v1 |
| Volume Number | 221 |
| Issue Number | 3 |
| Journal | The American journal of physiology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Carbohydrates Caseins Fructose GCK gene Glucose Jejunum KHK gene Sucrose casein kinase fructokinase activity hexokinase activity positive regulation of type IV pilus biogenesis |
| Content Type | Text |
| Resource Type | Article |
