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Volumetric Modulated Arc Therapy Treatment Protocol for Hypo-fractionated Stereotactic Body Radiotherapy for Localized Prostate Cancer
| Content Provider | Semantic Scholar |
|---|---|
| Author | Agazaryan, Nzhde Tenn, Stephen E. Chow, Poo Lee, Christopher Joon-Hai Lee, Percy P. Steinberg, Michael L. King, Christopher Ryan |
| Copyright Year | 2010 |
| Abstract | table rotations, collimator angle and photon beam energy have been investigated. Results: VMAT plans with ±45 degree collimator rotations required on average 38% less monitor units compared to plans with no collimator rotations and 20% less monitor units than plans with ±22.5 degree rotations. Plans with ±45 degree collimator rotations provided more homogeneous dose distribution with an average of 6% less maximal dose. VMAT plans with two arcs provided improved conformality and homogeneity with an average of 3% lower maximal dose compared to single arc plans. However, increasingthe number of arcsto threedid not provideany significantimprovement. Introductionof±5 and±10degree table rotations between arcs did not result in any significant dosimetric improvements. The selection of photon beam energy between 6MV and 10MV did not provide any notable dosimetric differences either. Conclusions: Thefinalselectionoftheprotocolincludes twocoplanar10MV RapidArcs with±45degreecollimatorrotations.This prospective clinical trial is designed to deliver 5 fractions of 8 Gy with the prescription dose covering the 95% of the planning target volume. The beam-on time for eachof the coplanar arcs is approximately 2 minutes.For the purpose ofintrafraction motionmanagement, two Rapid Arcs are further split to 4 half arcs with approximately one minute treatment time for each segment. The patient is stereoscopicallyimagedandrepositionedifnecessaryusingExacTracpriortothedeliveryofeacharc.Additionally,CBCTisobtained prior to eachfractionforthe purposesof confirmationofExacTracpositioningand volumetric evaluation of bladderand rectalfilling. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.ijrobp.2010.07.1953 |
| Volume Number | 78 |
| Alternate Webpage(s) | http://radonc.ucla.edu/workfiles/SBRT/Agazaryan_Poster_ASTRO_2010_Final_3.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/j.ijrobp.2010.07.1953 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
