Loading...
Please wait, while we are loading the content...
Similar Documents
Prevalencia de infección por virus de papiloma humano de alto riesgo oncogénico VPH-AR en mujeres embarazadas que acuden al control por consulta externa en el Hospital Gineco Obstétrico Isidro Ayora de la ciudad de Quito
| Content Provider | Semantic Scholar |
|---|---|
| Author | Guerra, María Belén Goyes Parra, Andrea Macías, Jéssica Monserrate Moreira |
| Copyright Year | 2015 |
| Abstract | Diagnosis and treatment of infection caused by Human Papilloma Virus and cancer associated to such virus are one of the major challenges of this decade. Main difficulties lies in the identification of viral genotype, absence of an effective antiviral therapy and high recurrence and persistence rates in spite of the therapy applied. Taking into account that pregnancy is a physiologic immunodeficiency situation and that no statistical data are provided as a reference for studies on such population in Ecuador, a study was conducted intended to determine prevalence of Human Papilloma Virus in our population to be used as a base to sustain future researches. Our transversal descriptive study was intended to determine prevalence of the high oncogenic risk Human Papilloma Virus (HR-HPV) through detection and genotyping with the polymerase chain reaction (PCR), in a group of 100 pregnant women between the second and third semester being admitted to the Hospital Gineco – Obstetrico “Isidro Ayora” of Quito city, for ambulatory health service, from September to December 2014. Results: Out of 100 pregnant women that took a part in the study, 49 patients were positive in the PCR test intended to detect the Human Papilloma Virus, out of which, 28 (57.1%) were positive for high risk; 16 (32.7%) for low oncogenic risk, and 5 (10.2%) were not gene-typified due to their low viral burden. Most of high risk genotypes were 16 (50%), 52 (29%) and 58 (14%), which provides a global prevalence of 28% for HRHPV. It allows us concluding that prevalence of HR-HPV in pregnant women is similar to that found in other studies; in our population it was 28%. Genotypes found were a sub-group of 5, out of which #16 was the most prevalent, which in the worldwide literature is associated to a higher risk of cervical cancer. Timely sieving should be promoted during pregnancy, because it is a good opportunity for early detection of a disorder. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.dspace.uce.edu.ec/bitstream/25000/4722/1/T-UCE-0006-109.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
