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New flavonoid glycosides and cyanogenic glycosides from Dracocephalum peregrinum.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Fu, Peng Zhao, Chunchao Tang, Jian Shen, Yunheng Xu, Xi-Ke |
| Copyright Year | 2009 |
| Abstract | Separation of ethyl acetate fractionation of Dracocephalum peregrinum afforded three new flavonoid glucosides (1-3), and a new cyanogenic glucoside (4). Their structures were elucidated based on HR-electron spray ionization (ESI)-MS, EI-MS, UV, IR, 1D-, and 2D-NMR data. 1-4 were tested in vitro for their antiinflammatory activity against the RAW 264.7, 293 cells. Among the compounds tested, 1-4 shown good antiinflammatory activity at 100 mug/ml by the measurement of nitric oxide (NO) in lipopolysaccharide (LPS) activated macrophages. But only 2 and 3 shown weak antiinflammatory activity at 100 mug/ml during the nuclear factor (NF)-kappaB activation assay. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.jstage.jst.go.jp/article/cpb/57/2/57_2_207/_pdf/-char/en |
| PubMed reference number | 19182414v1 |
| Volume Number | 57 |
| Issue Number | 2 |
| Journal | Chemical & pharmaceutical bulletin |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Anti-Inflammatory Agents Cyanogenic Glucoside F Factor Flavonoids Glycosides Lipopolysaccharides Mycobacterium peregrinum Nitric Oxide ethyl acetate flavonoid glucuronidation |
| Content Type | Text |
| Resource Type | Article |
