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Evaluation of pulmonary infiltrates in patients with haematological malignancies using fibreoptic bronchoscopy and bronchoalveolar lavage
| Content Provider | Semantic Scholar |
|---|---|
| Author | Shawgi, S. Kumar, Lalit Kochupillai, Vinod Shukla, Nootan Kumar Broor, Shobha Kapila, Kusum Banerjee, Uma Kapil, Arti Thulkar, Sanjay P. |
| Copyright Year | 2004 |
| Abstract | Background : Chest infection is the major cause of morbidity and mortality among patients with haematological malignancies. Conventional diagnostic methods – chest xray , blood and sputum culture have limited yield . We used fibreoptic bronchoscopy and bronchoalveolar lavage to evaluate nature of pulmonary infiltrates on chest xray. Patients and Methods : 25 patients with haematological malignancies with fever and pulmonary infiltrates were studied. Patients median age was 32 years, ranging from 16 to 65 years. There were 21 males and 4 females. Initial evaluation included – detailed physical examination including chest to see for any focus of infection. In all patients , base line blood counts (total and differential), chest x-ray and cultures from blood and other body fluids were taken before starting broad spectrum antibiotics . Those not responding over next 48-72 hours received gram positive coverage followed by amphotericin-B therapy . Patients with persistent fever and pulmonary infiltrates were subjected to fibre-optic bronchoscopy (FOB) and bronchoalveolar lavage (BAL) and samples were collected for bacterial, fungal, AFB and viral studies. The findings were correlated with Chest x-ray and CT scan. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://repository.ias.ac.in/66798/1/66798.pdf |
| Alternate Webpage(s) | http://medind.nic.in/ias/t04/i4/iast04i4p10.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |