NDLI: Use of zinc protoporphyrin in screening individuals for exposure to lead.

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Use of zinc protoporphyrin in screening individuals for exposure to lead.

Content Provider	Semantic Scholar
Author	Zwennis, Willem C. M. Franssen, Aem Wijnans, Marian
Copyright Year	1990
Abstract	We studied the relation between the concentrations of lead in blood (PbB) and zinc protoporphyrin in blood (ZPP) in a group of 801 men occupationally exposed for more than one year to lead or inorganic lead compounds. Linear regression of PbB on log ZPP provided 95% tolerance intervals for PbB values for a given ZPP value. The intervals we found are too large to warrant the estimation of PbB on the basis of ZPP measurements in health surveillance of lead workers. Instead we propose a procedure in which ZPP can be used as an indicator to decide which individuals exposed to lead need further investigation of PbB in light of existing limit values for PbB. The procedure is applicable only for PbB values of 2.4 mumol/L or more but may reduce considerably the costs for screening individuals or groups of people exposed to lead.
File Format	PDF HTM / HTML
DOI	10.1093/clinchem/36.8.1456
PubMed reference number	2387041
Journal	Medline
Volume Number	36
Issue Number	8
Part	1
Alternate Webpage(s)	http://clinchem.aaccjnls.org/content/clinchem/36/8/1456.2.full.pdf
Alternate Webpage(s)	https://doi.org/10.1093/clinchem%2F36.8.1456
Journal	Clinical chemistry
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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