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Molecular cloning of substance P receptor cDNA from guinea-pig uterus.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Gorbulev, V. G. Akhundova, A. A. Luzius, H. Fahrenholz, Falk |
| Copyright Year | 1992 |
| Abstract | A cDNA encoding guinea-pig uterine substance P (SP) receptor has been isolated using the homology screening approach. Northern blot analysis reveals that the corresponding mRNA, of approx. 4.8 kb, is expressed in all tissues tested, but predominantly in the uteri of non-pregnant animals; during pregnancy its expression is reduced. The guinea-pig SP receptor was expressed in COS-7 cells and demonstrated relative ligand affinity in the order: SP much greater than neurokinin A greater than neurokinin B. |
| Starting Page | 99 |
| Ending Page | 102 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0167-4781(92)90105-9 |
| PubMed reference number | 1374648 |
| Journal | Medline |
| Volume Number | 1131 |
| Issue Number | 1 |
| Alternate Webpage(s) | https://core.ac.uk/download/pdf/35098377.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/0167-4781%2892%2990105-9 |
| Journal | Biochimica et biophysica acta |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |