An uncommon case of diabetic mastopathy in type II non-insulin dependent diabetes mellitus.

Content Provider	Semantic Scholar
Author	Sotome, Keiichi Ohnishi, Tatsuya Miyoshi, Ryo Nakamaru, Makoto Furukawa, Akio Miyazaki, Hiroshi Morozumi, Kyoei Tanaka, Yoichi Iri, Hisami
Copyright Year	2006
Abstract	Diabetic mastopathy is an uncommon tumor-like proliferation of fibrous tissue of the breast that usually occurs in a patient who has suffered from type I diabetes mellitus of long duration. Here we report a rare case of diabetic mastopathy that occurred in type II non-insulin dependent diabetes mellitus. This patient was a 63-year-old postmenopausal woman. Mammography, ultrasonography and MR imaging could not distinguish it from breast cancer. Although the core needle biopsy specimen showed fibrosis without evidence of malignancy, excisional biopsy was performed. Histological findings demonstrated typical diabetic mastopathy with keloid-like fibrosis, perivascular lymphocytic infiltration, and lymphocytic lobulitis without evidence of malignancy. These lymphocytes were composed predominantly of B-cells. Five months after surgical biopsy, a nodular formation approximately 4 cm in diameter recurred adjacent to the resected end of the biopsy.
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.jstage.jst.go.jp/article/jbcs/13/2/13_2_205/_pdf/-char/ja
PubMed reference number	16755119v1
Volume Number	13
Issue Number	2
Journal	Breast cancer
Language	English
Access Restriction	Open
Subject Keyword	Biopsy Specimen Breast Diseases Core needle biopsy Diabetes Mellitus Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus, Non-Insulin-Dependent Diabetic Ketoacidosis Diabetic Nephropathy Diameter (qualifier value) Excision biopsy Fibrosis Keloid Mammary Neoplasms Mammography Mice, Inbred NOD Patients Small Lymphocytic Lymphoma
Content Type	Text
Resource Type	Article