Loading...
Please wait, while we are loading the content...
Similar Documents
Synthesis and In-vitro Activity of Some New Class of Thiazolidinone and Their Arylidene Derivatives
| Content Provider | Semantic Scholar |
|---|---|
| Author | Seelam, Nareshvarma Shrivastava, S. P. |
| Copyright Year | 2011 |
| Abstract | In an attempt to find a new class of anti microbial agents, a series of thiazolidinone and their 5-arylidene derivatives containing 4-(4-methyl benzamido)-benzoyl moiety were synthesized via the reaction of benzocaine with appropriate chemical reagents. These compounds were screened for their antibacterial activity against Gram-positive bacteria (Bacillus subtilis and Bacillus thuringiensis), Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and antifungal activity against Botrytis fabae, Fusarium oxysporan and Candida albicans. On the other hand the synthesized compounds were also screened for their anti tubercular activity. IR, NMR, NMR and MS spectral analyses established the structures of the newly synthesized compounds. The results revealed that some of these compounds have shown promising antimicrobial and anti tubercular activity in comparison with standard drugs. |
| Starting Page | 3996 |
| Ending Page | 4000 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.5012/bkcs.2011.32.11.3996 |
| Volume Number | 32 |
| Alternate Webpage(s) | http://ocean.kisti.re.kr/downfile/volume/chemical/JCGMCS/2011/v32n11/JCGMCS_2011_v32n11_3996.pdf |
| Alternate Webpage(s) | https://doi.org/10.5012/bkcs.2011.32.11.3996 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
