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Prevalence Of Antimicrobial Resistance And Characterization Of Resistance Genes In Escherichia Coli Isolates From Captive Baboons In Kenya
| Content Provider | Semantic Scholar |
|---|---|
| Author | Mureithi, Dominic K. |
| Copyright Year | 2011 |
| Abstract | The increasing prevalence o f antimicrobial resistance is a major public health problem globally. In Kenya and the rest of developing countries the problem of antimicrobial resistance is much pressing especially due to high levels of infectious diseases and cost constraints which prevent the widespread use of newer and more expensive agents. Multiple studies drawn from point-prevalence assessment have recognized the role of commensal bacteria in the spread of antimicrobial resistance. In veterinary medicine, the alarming state of bacterial antimicrobial resistance is seen in examining the Escherichia coli isolates, where attention has been given to food-producing animals such as pigs, cattle and domestic fowl. However, few studies have looked at the antimicrobial resistance profiles in non-human primates. Therefore this study had the objective of assessing antimicrobial drug susceptibility and genetic characteristics of antimicrobial resistance in Escherichia coli from non-human primates. A total of 100 faecal samples were collected using aseptic techniques from two groups of baboons at the Institute of Primate Research (IPR), Nairobi Kenya. Thirty six faecal samples were from group I baboons made up of 20 adult males and 16 females captured from Aberdare National park and transported to IPR one month earlier. Sixty four faecal samples were from group II baboons consisting of 64 adult male baboons that had lived at the IPR for a period of between one and 5 years. Ninety seven Escherichia coli were isolated by standard cultural, biochemical tests and final identification using the API 20E system (BioMe'rieux) test. Antimicrobial susceptibility was performed by the agar disk diffusion method as recommended by the Clinical and laboratory Standards Institute (CLSI). A total o f 16 antimicrobial agents commonly used were tested and these were: ampicillin 10 pg, piperacillin 100 pg, amoxyclav 30 pg. ceftriaxone 30 pg, ceftazidime 30 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://erepository.uonbi.ac.ke:8080/xmlui/bitstream/handle/11295/25379/Mureithi,%20Dominic%20K_Prevalence%20of%20antimicrobial%20resistance%20and%20characterization%20of%20resistance%20genes%20in%20escherichia%20col!%20Isolates%20from%20captive%20baboons%20in%20kenya.pdf?isAllowed=y&sequence=3 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
