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Imaging of bone diseases in children using Ultrasonic Computed Tomography
| Content Provider | Semantic Scholar |
|---|---|
| Copyright Year | 2017 |
| Abstract | For children bone pathologies (tumours, non-union fractures, distraction), the development of ultrasonic imaging modality and protocols is an important challenge to provide an alternative to conventional modalities such as X-ray radiology or MRI which are limited in case of children's examination due to radiation problem, to the often required anaesthesia, or to some behaviour disturbances [1]. Furthermore, ultrasounds could be used as therapeutic vector in the context of bone repair, leading to a theranostic issue. The locks associated with the in vivo configuration are numerous: accessibility of anatomical sites, attenuation due to soft tissue resolution, paired bones. For several years, the "Waves and Imaging" Group of The Laboratory of Mechanics and Acoustics (LMA-CNRS) has been studying the ultrasonic computed tomography (analogous to echography for the physics of wave propagation and with the X-ray tomography for the inverse problem) [2] of children bone tissues. An experimental device was developed and tested in academic configurations [3] (Figure 1). To take into account the important parameters of the in vivo theranostic process and to integrate them into the device and the associated protocol, we use a multiphysics modelling with finite element methods [4] developed by the Biomechanics Group of the Institute of Movement Sciences (ISM). This model allows to interpret more accurately the experimental results and guide the development of the prototype to clinical application. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://doc2amu.univ-amu.fr/sites/doc2amu.univ-amu.fr/files/project-files/thesis.project-lasaygues.baron_.doc2amu.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
