NDLI: Acceleration of the ventricular response during atrial fibrillation in the Wolff-Parkinson-White syndrome after verapamil.

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Acceleration of the ventricular response during atrial fibrillation in the Wolff-Parkinson-White syndrome after verapamil.

Content Provider	Semantic Scholar
Author	Gulamhusein, Sajad S.
Copyright Year	1982
Abstract	We examined the electrophysiologic effects of verapamil in eight patients with the Wolff-Parkinson-White syndrome. Verapamil shortened the antegrade effective refractory period of the accessory pathway in three patients and abbreviated the shortest cycle length with 1:1 conduction over the accessory pathway in two patients. More significantly, verapamil decreased the shortest RR interval between preexcited ventricular complexes during atrial fibrillation (279 +/- 20 msec vs 236 +/- 18 msec, mean +/- SEM; p less than 0.01). After verapamil, two patients required cardioversion for hemodynamic deterioration after acceleration of the ventricular response during atrial fibrillation. In the four patients with predominantly preexcited ventricular complexes during atrial fibrillation the ventricular rate accelerated after verapamil, whereas in patients with predominantly normal ventricular complexes, the average ventricular rate decreased or did not change after verapamil. Verapamil may result in significant acceleration of ventricular response during atrial fibrillation in the Wolff-Parkinson-White syndrome. The safety of verapamil in individual patients with the Wolff-Parkinson-White syndrome should be established by electrophysiologic testing before its use.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://circ.ahajournals.org/content/circulationaha/65/2/348.full.pdf
Alternate Webpage(s)	http://circ.ahajournals.org/content/circulationaha/65/2/348.full.pdf?download=true
PubMed reference number	7053894v1
Volume Number	65
Issue Number	2
Journal	Circulation
Language	English
Access Restriction	Open
Subject Keyword	Accessory Atrioventricular Bundle (disorder) Atrial Fibrillation Heart Atrium Hemodynamics Parkinsonian Disorders Patients Short Ventricular Fibrillation Verapamil Wolff-Parkinson-White Syndrome
Content Type	Text
Resource Type	Article

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