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Antibacterial and immunomodulatory activities of bovine lactoferrin against Escherichia coli O157:H7 infections in cattle
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kieckens, E. Rybarczyk, Joanna Cox, Eric Vanrompay, Daisy C. G. |
| Copyright Year | 2018 |
| Abstract | Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a zoonotic pathogen that causes food-borne disease in humans ranging from watery diarrhea to bloody diarrhea and severe hemorrhagic colitis, renal failure and hemolytic uremic syndrome. Cattle, the most important source of E. coli O157:H7 transmission to humans, harbor the bacteria in their gastrointestinal tract without showing clinical symptoms. Prevention of E. coli O157:H7 infections in ruminants could diminish the public health risk. However, there is no specific treatment available nor a vaccine or a therapeutic agent which completely prevents E. coli O157:H7 infections in cattle. This paper provides an overview of latest research data on eradicating enterohemorrhagic E. coli O157:H7 in ruminants by use of bovine lactoferrin administration. The article provides insights into the anti-microbial and immunomodulatory activities of bovine lactoferrin against E. coli O157:H7 infections in cattle. |
| Starting Page | 321 |
| Ending Page | 330 |
| Page Count | 10 |
| File Format | PDF HTM / HTML |
| DOI | 10.1007/s10534-018-0082-x |
| Alternate Webpage(s) | https://biblio.ugent.be/publication/8571432/file/8571433 |
| PubMed reference number | 29442205 |
| Alternate Webpage(s) | https://doi.org/10.1007/s10534-018-0082-x |
| Journal | Medline |
| Volume Number | 31 |
| Journal | BioMetals |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
