"Turn-on" fluorescent chemosensor for zinc(II) dipodal ratiometric receptor: application in live cell imaging.

Content Provider	Semantic Scholar
Author	Tayade, Kundan C. Bondhopadhyay, Banashree Sharma, Hemant Basu, Anupam Gite, Vikas V. Attarde, Sanjay B. Singh, Narinder Kuwar, Anil S.
Copyright Year	2014
Abstract	A dipodal ligand 2,2'-((ethane-1,2-diylbis(azanediyl))bis(ethane-1,1-diyl))diphenol was synthesized through a condensation reaction and was characterized with IR, (1)H NMR, (13)C-NMR, and mass spectroscopy. The receptor 2 has shown marked enhancement in fluorescence intensity (emission signal at 341 nm) on binding with Zn(2+) as compared to other surveyed metal ions. The sensor has shown dramatic changes in dual channel fluorescence emission with λmax at 300 and 341 nm. The successive addition of Zn(2+) to the solution of the sensor led to a blue shift of the peak maxima and interestingly upon addition of higher equivalents of Zn(2+) quenched the fluorescence intensity of the sensor, and ultimately the original fluorescent profile of sensor was restored. The structures of 2 and 3 were optimized with B3LYP/LanL2DZ basis sets. The receptor 2 successfully detect the Zn(2+) ion in HeLa cells cultured in Zn(2+) enriched medium.
File Format	PDF HTM / HTML
DOI	10.1039/c4pp00034j
PubMed reference number	24828211
Journal	Medline
Volume Number	13
Issue Number	7
Alternate Webpage(s)	https://pubs.rsc.org/en/content/getauthorversionpdf/C4PP00034J
Alternate Webpage(s)	http://www.rsc.org/suppdata/pp/c4/c4pp00034j/c4pp00034j1.pdf
Alternate Webpage(s)	https://doi.org/10.1039/c4pp00034j
Journal	Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article