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El paracetamol podría ser útil en el tratamiento del ductus arterioso persistente en el recién nacido de muy bajo peso
| Content Provider | Semantic Scholar |
|---|---|
| Author | Domínguez, María Eugenia Pérez Rodríguez, Sonia Rivero Rodrigo, Fermín García-Muñoz |
| Copyright Year | 2015 |
| Abstract | Patent ductus arteriosus (PDA) is frequently found in preterm newborns and its incidence increases with lower gestational age (GA), rising up to 60% in neonates of gestational ages 26 weeks and less. Clinically, it is associated with an increase in morbidity and mortality, including pulmonary oedema and haemorrhage, intraventricular haemorrhage (IVH), necrotising enterocolitis (NEC), bronchopulmonary dysplasia (BPD) and retinopathy of prematurity. The treatment of PDA includes fluid restriction, diuretics, nonselective cyclooxygenase (COX) inhibitors (indomethacin or ibuprofen) and, if all these fail, surgical closure. Recently, several authors have proposed the use of paracetamol for pharmacological closure of PDA if traditional medications fail or are contraindicated. As far as we know, there is no evidence on the use of paracetamol for this purpose in extremely preterm newborns in Spain. We present the cases of two patients with haemodynamically significant ductus (hsPDA) with contraindications for the administration of ibuprofen in which we tried alternative treatment with paracetamol before surgical closure. Cases (Table 1) |
| Starting Page | 362 |
| Ending Page | 363 |
| Page Count | 2 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.anpedi.2014.07.018 |
| Volume Number | 82 |
| Alternate Webpage(s) | http://www.analesdepediatria.org/index.php?p=revista&pii=S1695403314004019&tipo=pdf-simple |
| Alternate Webpage(s) | https://www.analesdepediatria.org/index.php?p=revista&pii=S234128791500099X&tipo=pdf-simple |
| Alternate Webpage(s) | https://doi.org/10.1016/j.anpedi.2014.07.018 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
