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Middle Cerebral Artery Atherosclerotic Plaques in Recent Small Subcortical Infarction: A Three-Dimensional High-resolution MR Study
| Content Provider | Semantic Scholar |
|---|---|
| Author | Zou, Xiao-Dong Chung, Yiu-Cho Zhang, Lei Han, Ying Yang, Qi Jia, Jianping |
| Copyright Year | 2015 |
| Abstract | PURPOSE Conventional two-dimensional vessel wall imaging has been used to depict the middle cerebral artery (MCA) wall in patients with recent small subcortical infarctions (RSSIs). However, its clinical use has been limited by restricted spatial coverage, low signal-to-noise ratio (SNR), and long scan time. We used a novel three-dimensional high-resolution MR imaging (3D HR-MRI) technique to investigate the presence, locations, and contrast-enhanced patterns of MCA plaques and their relationship with RSSI. METHODS Nineteen consecutive patients with RSSI but no luminal stenosis on MR angiography were prospectively enrolled. 3D HR-MRI was performed using a T1w-SPACE sequence at 3.0 T. The presence, locations, and contrast-enhanced patterns of the MCA plaques on the ipsilateral and contralateral sides to the RSSI were analyzed. RESULTS Eighteen patients successfully completed the study. MCA atherosclerotic plaques occurred more frequently on the ipsilateral than the contralateral side to the RSSI (72.2% versus 33.3%, P = 0.044). The occurrence of superiorly located plaques was significantly higher on the ipsilateral than the contralateral side of the MCA (66.7% versus 27.8%; P = 0.044). CONCLUSIONS Superiorly located plaques are closely associated with RSSI. 3D high-resolution vessel wall imaging may be a potential tool for etiologic assessment of ischemic stroke. |
| File Format | PDF HTM / HTML |
| DOI | 10.1155/2015/540217 |
| PubMed reference number | 26539508 |
| Journal | Medline |
| Volume Number | 2015 |
| Alternate Webpage(s) | http://downloads.hindawi.com/journals/bmri/2015/540217.pdf |
| Alternate Webpage(s) | http://ftp.ncbi.nlm.nih.gov/pub/pmc/74/f3/BMRI2015-540217.PMC4619811.pdf |
| Alternate Webpage(s) | https://doi.org/10.1155/2015%2F540217 |
| Journal | BioMed research international |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |