Loading...
Please wait, while we are loading the content...
Copper-Catalyzed P-H Insertions of α-Imino Carbenes for the Preparation of 3-Phosphinoylindoles.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wang, Lisheng Liu, Yang Yang, Hua Liu, Xu Wen Wang, Jianyi Li, Xiaoxun Jiang, Jun |
| Copyright Year | 2017 |
| Abstract | A highly efficient P-H insertion of α-imino copper carbene into H-phosphine oxides, leading to 3-phosphinoylindoles with a broad substrate diversity and good chemoselectivity, is established. This methodology provides a rapid and efficient approach for the C (sp2)-P bond formation via the P-H insertion strategy. The stereoselective P-H insertion of α-imino copper carbene represents a unique example of asymmetric P-H insertion, affording P-stereogenic 3-phosphinoylindoles with high stereoselectivities. |
| Starting Page | 782 |
| Ending Page | 785 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://s3-eu-west-1.amazonaws.com/pstorage-acs-6854636/7449037/ol6b03752_si_001.pdf |
| PubMed reference number | 28145720v1 |
| Alternate Webpage(s) | https://doi.org/10.1021/acs.orglett.6b03752 |
| DOI | 10.1021/acs.orglett.6b03752 |
| Journal | Organic letters |
| Volume Number | 19 |
| Issue Number | 4 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Amine Oxidase (Copper-Containing) Clinical act of insertion Cyclic N-Oxides Insertion Mutation Oxides carbene phosphine |
| Content Type | Text |
| Resource Type | Article |
