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Immunization with PspA incorporated into a poly(ethylene oxide) matrix elicits protective immunity against Streptococcus pneumoniae.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Johnson, LaShundra Repka, Michael McDaniel, Larry S. |
| Copyright Year | 2007 |
| Abstract | CBA/N mice were immunized with PspA in a poly(ethylene oxide) matrix to examine its ability to deliver the antigen and modulate the immune response. All mice receiving PspA in the matrix survived a lethal pneumococcal challenge and had serum anti-PspA antibody levels statistically higher than mice receiving PspA alone (P < 0.009). |
| File Format | PDF HTM / HTML |
| DOI | 10.1128/CVI.00082-07 |
| PubMed reference number | 17460113 |
| Journal | Medline |
| Volume Number | 14 |
| Issue Number | 6 |
| Alternate Webpage(s) | http://cvi.asm.org/content/14/6/789.full.pdf |
| Alternate Webpage(s) | https://doi.org/10.1128/CVI.00082-07 |
| Journal | Clinical and vaccine immunology : CVI |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |