P2O5/SiO2 as an efficient heterogeneous catalyst for the synthesis of heterocyclic alkene derivatives under thermal solvent-free conditions

Content Provider	Semantic Scholar
Author	Siddiqui, Zeba N. Khan, Tabassum
Copyright Year	2013
Abstract	A highly efficient methodology is developed for the synthesis of a series of heterocyclic alkene derivatives 3a–k from 5-chloro-3-methyl-1-phenylpyrazole-4-carboxaldehyde 1 and active methylene compounds 2a–k, in the presence of P2O5/SiO2, under thermal solvent-free conditions, in high yields, within a short reaction time. The catalyst is characterized for the first time by using X-ray diffraction (XRD), scanning electron microscopy–energy dispersive X-ray (SEM-EDX) and transmission electron microscopy (TEM). The stability of the catalyst is evaluated by thermogravimetric analysis/differential thermal analysis (TG/DTA) and differential scanning calorimetry (DSC) techniques. The molecular structure of alkene 3a is confirmed by single crystal X-ray diffraction. The advantages of the present methodology are excellent yields of products, recyclability of the catalyst and an easy operational procedure.
Starting Page	2032
Ending Page	2043
Page Count	12
File Format	PDF HTM / HTML
DOI	10.1039/C3CY00095H
Volume Number	3
Alternate Webpage(s)	http://www.rsc.org/suppdata/cy/c3/c3cy00095h/c3cy00095h.pdf
Alternate Webpage(s)	https://doi.org/10.1039/C3CY00095H
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article