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A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds
| Content Provider | Semantic Scholar |
|---|---|
| Author | Cattalini, Juan Pablo García, Javier Sangorrín Boccaccini, Aldo Roberto Lucangioli, Silvia Edith Mouriño, Viviana Silvia |
| Copyright Year | 2013 |
| Abstract | Abstract A biomaterial with bioactive glass nanoparticles (nBG) and Ca 2+ incorporated into alginate matrix was developed. Films characterization was carried out by SEM, IR, tensile strength measurements, bioactivity assay, degradation and swelling studies. Ca 2+ release from films was analyzed. Freeze-dried-scaffolds were also fabricated. Films showed the development of a homogeneous matrix and the mechanical properties were improved when nBG were incorporated. The bioactive nature of nBG containing films was confirmed by studies in simulated body fluid. Degradation was negligible and a good swelling capacity was observed. Moreover Ca 2+ was released in a controlled manner. In scaffolds fabricated by freeze-drying, pores were seen to be uniform and well distributed. According to the characterization results, these composite biomaterials are attractive candidates for the fabrication of bone tissue engineering scaffolds. |
| Starting Page | 78 |
| Ending Page | 84 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.proeng.2013.05.096 |
| Volume Number | 59 |
| Alternate Webpage(s) | http://ri.conicet.gov.ar/bitstream/handle/11336/1927/1-s2_0-S1877705813010102-main.pdf?isAllowed=y&sequence=1 |
| Alternate Webpage(s) | https://doi.org/10.1016/j.proeng.2013.05.096 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
