Properties and Risk of the Use of Bisphenol A−Glycidyl Methacrylate and Urethane Dimethacrylate – Basic Monomers of Dental Restorative Materials

Content Provider	Semantic Scholar
Author	Pawlowska, Elzbieta Loba, Katarzyna Błasiak, Janusz Szczepańska, Joanna
Copyright Year	2009
Abstract	Restorative dentistry uses methacrylate resin−based materials which can be bonded to the tooth structure. The initial clinical success of these materials partly put aside the concern about biological risk associated with their use, becau− se it was assumed that these materials are in the form of polymers tightly bound to the tooth structure. However, the process of polymerization not always is complete and the polymer itself may release monomers, which can penetra− te oral cavity and pulp, from where they can reach virtually any organ of the organism. The local concentration of monomers can be in the millimolar range, high enough to induce a variety of adverse biological effects. A large bo− dy of evidence suggest that monomers resulting from incomplete polymerization or released from the polymer may exert cytotoxic and genotoxic effects. Bisphenol A−glycidyl methacrylate (Bis−GMA) and urethane dimethacrylate (UDMA) are basic monomers used in forming dental restorative composites. They may induce several undesired ef− fects, affecting immunological and nervous systems, promoting mutations and genomic instability. Therefore, there is a need to intensify the research on adverse biological effects of methacrylate monomers and on efficient protec− tion of dental personnel and patients against such effects (Dent. Med. Probl. 2009, 46, 4, 477–485).
Starting Page	477
Ending Page	485
Page Count	9
File Format	PDF HTM / HTML
Volume Number	46
Alternate Webpage(s)	http://www.dmp.umed.wroc.pl/pdf/2009/46/4/477.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article