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Body weight rhythmicity in the unweaned female rat following neonatal estrogen treatment
| Content Provider | Semantic Scholar |
|---|---|
| Author | Fernández-Galaz, Carmen Delgado, V. Tejero, Alberto |
| Copyright Year | 1990 |
| Abstract | Male and female rats were weighted daily throughout this study to determine whether neonatal exposure to estrogens influences body weight (BW) patterns, particularly during the period before weaning when vaginal opening (VO) occurs as a consequence of this treatment. Females receiving estradiol benzoate (EB) at the age of 5 days had greater body weight than their controls soon after the treatment and until day 21. Clear 3-day periodic changes of BW, between days 9 and 20, were revealed by the spectral analysis of the results in EB-given females which did not occur in their controls. Changes of BW (at 4-day intervals) were verified in adult control females whereas age-matched EB-treated females did not show such a rhythm. Neither BW gain nor infradian rhythmicity were detected in infantile males after neonatal EB treatment. The results suggest that, as in spontaneous puberty, a relationship between the occurrence of VO and the establishment of the infradian body rhythmicity in the infantile estrogenized female may exist. |
| Starting Page | 273 |
| Ending Page | 276 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0031-9384(90)90312-R |
| PubMed reference number | 2255731 |
| Journal | Medline |
| Volume Number | 48 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/003193849090312R |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/003193849090312R?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0031-9384%2890%2990312-R |
| Journal | Physiology & Behavior |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |