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Site-selective installation of BASHY fluorescent dyes to Annexin V for targeted detection of apoptotic cells.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Cal, Pedro Sieglitz, Florian Santos, Fábio Miguel Figueiredo Carvalho, Cátia Parente Guerreiro, Ana Bertoldo, Jean B. Pischel, Uwe Gois, Pedro M. P. Bernardes, Gonçalo J. L. |
| Copyright Year | 2016 |
| Abstract | Fluorophores are indispensable for imaging biological processes. We report the design and synthesis of azide-tagged boronic acid salicylidenehydrazone (BASHY) dyes and their use for site-selective labelling of Annexin V. The Annexin V-BASHY conjugate maintained function and fluorescence as demonstrated by the targeted detection of apoptotic cells. |
| Starting Page | 368 |
| Ending Page | 371 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://pubs.rsc.org/en/content/articlepdf/2016/cc/c6cc08671c?page=search |
| Alternate Webpage(s) | http://gbernardeslab.com/wp/wp-content/uploads/2016/12/CC_2017-368.pdf |
| Alternate Webpage(s) | http://pubs.rsc.org/en/content/articlepdf/2017/cc/c6cc08671c |
| PubMed reference number | 27935613v1 |
| Alternate Webpage(s) | https://doi.org/10.1039/c6cc08671c |
| DOI | 10.1039/c6cc08671c |
| Journal | Chemical communications |
| Volume Number | 53 |
| Issue Number | 2 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Annexins Azides Dyes Fluorescence Fluorescent in Situ Hybridization Immunostimulating conjugate (antigen) Thioctic Acid Tracer boronic acid |
| Content Type | Text |
| Resource Type | Article |
