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The effects of pupil size on the multifocal electroretinogram
| Content Provider | Semantic Scholar |
|---|---|
| Author | González, Paola Parks, Steven Dolan, F. Keating, David |
| Copyright Year | 2004 |
| Abstract | This is an investigation of the effect of changing the pupil diameter on the P1 amplitude and latency of the multifocal electroretinogram (mfERG). MfERGs were recorded using a custom built wide field electrophysiological system. An array of 61 empirically scaled hexagons was used to stimulate the visual field. The duration of overall recording period was 8 min, segmented into 16 intervals each lasting 30 s. A combination of mydriatics and miotics were used to pharmacologically alter the pupil size and diameters between 1 and 10 mm were measured. There was a reduction in mfERG P1 amplitude in some cases greater than 50 (mfERG P1 amplitude 53 nV at 8 mm to 25 nV at 1 mm), with a change in pupil diameter of 7 mm. The mfERG P1 latency increased in some cases by as much as 8 ms in the central 40° (mfERG P1 latency 39 ms at 8 mm to 47 ms at 1 mm). These results suggest that pupil size has significant effects on mfERG P1 amplitude and latency. |
| Starting Page | 67 |
| Ending Page | 72 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1007/s10633-004-1545-7 |
| PubMed reference number | 15675201 |
| Journal | Medline |
| Volume Number | 109 |
| Alternate Webpage(s) | https://page-one.springer.com/pdf/preview/10.1007/s10633-004-1545-7 |
| Alternate Webpage(s) | https://doi.org/10.1007/s10633-004-1545-7 |
| Journal | Documenta Ophthalmologica |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |