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Enteroaggregative Escherichia coli (EAEC)
| Content Provider | Semantic Scholar |
|---|---|
| Author | Elias, Waldir P. Navarro-García, Fernando |
| Copyright Year | 2016 |
| Abstract | Enteroaggregative Escherichia coli (EAEC) is defined by the production of the characteristic aggregative adherence pattern on cultured epithelial cells. This pathotype is a food-borne emerging enteropathogen, responsible for cases of acute and persistent diarrhea in children and immunocompromised patients in developing countries, as well as in travelers returning from endemic areas. Growth and cognitive impairment are linked to EAEC infections in children living in developing countries. The pathogenesis of EAEC is characterized by abundant adherence to the intestinal mucosa, elaboration of enterotoxins/cytotoxins, and induction of mucosal inflammation. Several putative virulence factors associated with these three steps have been identified and characterized, but none of them is present in all strains. The virulence gene(s) that define virulent strains within this complex heterogeneity is yet to be determined. An increasing attention to this pathotype emerged since the massive outbreak caused by a hybrid hypervirulent Shiga toxin-expressing EAEC strain with severe clinical consequences. |
| Starting Page | 27 |
| Ending Page | 57 |
| Page Count | 31 |
| File Format | PDF HTM / HTML |
| DOI | 10.1007/978-3-319-45092-6_2 |
| Alternate Webpage(s) | https://www.aphl.org/conferences/proceedings/Documents/2018/PulseNet_OutbreakNet_EAEC%20ETEC_GC_01162019.pdf |
| Alternate Webpage(s) | https://doi.org/10.1007/978-3-319-45092-6_2 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
