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Terezine E, bioactive prenylated tryptophan analogue from an endophyte of Centaurea stoebe.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Abdou, Randa Shabana, Samah Rateb, Mostafa E. |
| Copyright Year | 2018 |
| Abstract | Fungal endophytes are considered promising sources of new bioactive natural products. In this study, a Mucor sp. has been isolated as an endophyte from the medicinal plant Centaurea stoebe. Through bioactivity-guided fractionation, the isolation of the new bioactive terezine E in addition to the previously reported 14-hydroxyterezine D was carried out. The isolated compounds were fully characterised by HRESIMS and 1D and 2D NMR analyses. Both compounds exhibited potent antiproliferative activity against K-562 and HUVEC cell lines and antifungal efficacy against the tested fungal strains. |
| Starting Page | 1 |
| Ending Page | 8 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| DOI | 10.1080/14786419.2018.1489393 |
| Alternate Webpage(s) | https://myresearchspace.uws.ac.uk:8443/ws/portalfiles/portal/10730527/2018_06_12_Abdou_Terezine_E.pdf |
| PubMed reference number | 30092665 |
| Alternate Webpage(s) | https://doi.org/10.1080/14786419.2018.1489393 |
| Journal | Medline |
| Journal | Natural product research |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |