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MAPKAP kinases — MKs — two's company, three's a crowd
| Content Provider | Semantic Scholar |
|---|---|
| Author | Gaestel, Matthias |
| Copyright Year | 2006 |
| Abstract | Downstream of mitogen-activated protein kinases (MAPKs), three structurally related MAPK-activated protein kinases (MAPKAPKs or MKs) — MK2, MK3 and MK5 — signal to diverse cellular targets. Although there is no known common function for all three MKs, these kinases are involved in important processes: MKs regulate gene expression at the transcriptional and post-transcriptional level, control cytoskeletal architecture and cell-cycle progression, and are implicated in inflammation and cancer. |
| Starting Page | 120 |
| Ending Page | 130 |
| Page Count | 11 |
| File Format | PDF HTM / HTML |
| DOI | 10.1038/nrm1834 |
| Alternate Webpage(s) | https://www2.mh-hannover.de/fileadmin/institute/physiologische_chemie/2006_nrm_7-120.pdf |
| PubMed reference number | 16421520 |
| Alternate Webpage(s) | https://doi.org/10.1038/nrm1834 |
| Journal | Medline |
| Volume Number | 7 |
| Journal | Nature Reviews Molecular Cell Biology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |