NDLI: Estudos de polimorfismos dos genes KIR e HLA em sangue de cordão umbilical e placentário (SCUP) de recém-nascidos a termo e pré-termo

Content Provider	Semantic Scholar
Author	Porcello, Laura Bertoldi
Copyright Year	2014
Abstract	Introdução: O nascimento pré-termo permanece sendo grande causa de mortalidade neonatal. A vulnerabilidade dos prematuros se dá principalmente pela imaturidade imunológica e infecções neonatais, que aumentam a probabilidade de complicações e prolongam o tempo de internação. A atividade das células Natural Killer (NK) em prematuros está reduzida e associada a maior susceptibilidade a agentes infecciosos. As células NK são capazes de mediar a resposta do sistema imune inato contra células infectadas por vírus e células malignas transformadas, podendo provocar um ataque direto às células alvo. Os principais receptores das células NK são os KIR (killer immunoglobulinlike-receptors), que reconhecem moléculas de HLA classe I.
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://lume.ufrgs.br/bitstream/handle/10183/113736/Poster_36279.pdf?isAllowed=y&sequence=2
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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