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Quantitative analysis of taste bud cell numbers in fungiform and soft palate taste buds of mice
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ohtubo, Yoshitaka Yoshii, Kiyonori |
| Copyright Year | 2011 |
| Abstract | Mammalian taste bud cells (TBCs) consist of several cell types equipped with different taste receptor molecules, and hence the ratio of cell types in a taste bud constitutes the taste responses of the taste bud. Here we show that the population of immunohistochemically identified cell types per taste bud is proportional to the number of total TBCs in the taste bud or the area of the taste bud in fungiform papillae, and that the proportions differ among cell types. This result is applicable to soft palate taste buds. However, the density of almost all cell types, the population of cell types divided by the area of the respective taste buds, is significantly higher in soft palates. These results suggest that the turnover of TBCs is regulated to keep the ratio of each cell type constant, and that taste responsiveness is different between fungiform and soft palate taste buds. |
| Starting Page | 13 |
| Ending Page | 21 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.brainres.2010.10.060 |
| PubMed reference number | 20971092 |
| Journal | Medline |
| Volume Number | 1367 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/S0006899310023292 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/S0006899310023292?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/j.brainres.2010.10.060 |
| Journal | Brain Research |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
