NDLI: CCK-8-immunoreactivity distribution in human brain: selective decrease in the substantia nigra from parkinsonian patients

Content Provider	Semantic Scholar
Author	Studler, J. M. Cesselin, François Legrand, Jean Claude Agid, Yves
Copyright Year	1982
Abstract	The regional distribution of immunoassayable CCK-8 was determined in 12 regions of control and parkinsonian human brain, with specific attention to the possible regional coexistence of CCK-8 with dopamine. In Parkinson's disease, CCK-8-I levels were only decreased in the substantia nigra where dopamine cell bodies lie, and not in striatal and corticolimbic dopamine projecting areas. Our results suggest that the major proportion of dopaminergic neurones degenerated in Parkinson's disease may not contain the CCK-8 peptide.
Starting Page	176
Ending Page	179
Page Count	4
File Format	PDF HTM / HTML
DOI	10.1016/0006-8993(82)91135-0
PubMed reference number	6288173
Journal	Medline
Volume Number	243
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/0006899382911350
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/0006899382911350?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://doi.org/10.1016/0006-8993%2882%2991135-0
Journal	Brain Research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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CCK-8-immunoreactivity distribution in human brain: selective decrease in the substantia nigra from parkinsonian patients